Descrição
Nanoindentation is ideal for the characterization of inhomogeneous biological materials. However, the use of nanoindentation techniques in biological systems is associated with some distinctively different techniques and challenges. For example, engineering materials used in the microelectronics industry (e.g. ceramics and metals) for which the technique was developed, are relatively stiff and exhibit time-independent mechanical responses. Biological materials, on the other hand, exhibit time-dependent behavior, and can span a range of stiffness regimes from moduli of Pa to GPa ¡ª eight to nine orders of magnitude. As such, there are differences in the selection of instrumentation, tip geometry, and data analysis in comparison with the ¡°black box¡± nanoindentation techniques as sold by commercial manufacturers. The use of scanning probe equipment (atomic force miscroscopy) is also common for small-scale indentation of soft materials in biology.
Contents:
Indentation and Adhesion at Small Length Scales (R F Cook)
Instrumentation and Experimentation (K J Van Vliet)
Mechanics of Adhesion (R F Cook)
Mechanics of Indentation (M L Oyen)
Computational Modeling of Indentation (X Chen)
Nanoindentation of Bone (V L Ferguson & S E Olesiak)
Nanoindentation of Tooth Tissues (L-H He & M V Swain)
Nanoindentation of Soft Tissues and Other Biological Materials (D M Ebenstein)
Cells and Membranes (K-K Liu & K-T Wan)
