Descrição
CONTENTS.:
Chapter 1|14 pages Ethical and Regulatory Approval for Human Studies – Chapter 2|16 pages Instrumentation, Imaging, Data Analysis and Display Chapter 3|10 pages – Good Manufacturing Practice in the Preparation of Pharmaceutical Dosage Forms for Scintigraphic Evaluation Chapter 4|16 pages Drug Delivery to the Respiratory Tract Chapter 5|14 pages Scintigraphic Study of Oesophageal Transit and Retention Chapter 6|30 pages Scintigraphic Study of Drug Delivery to the Stomach and Small Bowel Chapter 7|14 pages Scintigraphic Study of Colonic Release and Absorption Chapter 8|18 pages Scintigraphic Study of Ocular Drug Delivery Chapter 9|46 pages Scintigraphic Study of Drug Carriers and Conjugates
This text defines the role and scope of nuclear medicine imaging techniques (gamma scintigraphy) in pharmaceutical research, giving information from clinical trial data. No other technique can localize so precisely the site of disintegration of a tablet in the gastro-intestinal tract, the penetration of an aerosol in the lung or the residence time of a drug on the cornea. The book covers all aspects of scintigraphic imaging applied to pharmaceutical research, ranging from the regulatory requirements, ethical submission, and study approval in normal human subjects and patients groups, through to detailed descriptions of specific applications. It provides descriptions of the basic instrumentation, techniques, the principles of GMP applied to radiolabelling procedures and the importance of validation of products and procedures.
por
- Capa dura : 178 paginas
- ISBN-10 : 0748406883
- ISBN-13 : 9780748406883
- Livro sem uso, com paginas amareladas e um pouco sujas pelo tempo – capa, contracapa, bordas e paginas integras. sem marcas, grifos, marcações ou qualquer tipo de detalhe que possa interferir na leitura ou pesquisa – Conteudo perfeito
